Sequence determination of the Crimean–Congo hemorrhagic fever virus L segment

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assessment of recombination in the s-segment genome of crimean-congo hemorrhagic fever virus in iran

background: crimean-congo hemorrhagic fever virus (cchfv) belongs to genus nairovirus and family bunyaviridae. the main aim of this study was to investigate the extent of recombination in s-segment genome of cchfv in iran. methods: samples were isolated from iranian patients and those available in genbank, and analyzed by phyloge­netic and bootscan methods. results: through comparison of the ph...

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The main aim of this study was to obtain the Crimean-Congo hemorrhagic fever virus (CCHFV) glycoprotein, through either stable transgenic plants or using a transient expression system, and determine the yield, quality and finally the immunogenicity of the plant-made CCHFV glycoprotein in a mouse model. We designed and synthesized a codon-optimized G1/G2 gene from the G1 and G2 parts of the CCHF...

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Genetic Characterization of the M RNA Segment of Crimean Congo Hemorrhagic Fever Virus Strains, China

We report the genetic characterization of the M RNA segment of Crimean Congo hemorrhagic fever virus (CCHFV). Two CCHFV strains isolated in Xinjiang Province, a region endemic for CCHF in northwestern China, were studied. These strains, designated BA66019 and BA8402, were isolated in 1965 and 1984 from a CCHF patient and Hyalomma ticks, respectively. Viral RNA was extracted from suckling mouse ...

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Assessment of Recombination in the S-segment Genome of Crimean-Congo Hemorrhagic Fever Virus in Iran.

BACKGROUND Crimean-Congo Hemorrhagic Fever Virus (CCHFV) belongs to genus Nairovirus and family Bunyaviridae. The main aim of this study was to investigate the extent of recombination in S-segment genome of CCHFV in Iran. METHODS Samples were isolated from Iranian patients and those available in GenBank, and analyzed by phylogenetic and bootscan methods. RESULTS Through comparison of the ph...

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ژورنال

عنوان ژورنال: Virology

سال: 2004

ISSN: 0042-6822

DOI: 10.1016/j.virol.2003.09.046